Wed, Nov 29, 2023
Volume 3, Issue 3 (Autumn 2005)
ASJ 2005, 3(3): 163-171 |
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Sadeghi Y, Piryaee A, Almasi Tork S, Roozbehi A. Ultrastructural Study of Cadmium Effects on Photoreceptors and Ganglionic Cells of Retinal Layer in Mice Embryo. ASJ 2005; 3 (3) :163-171
URL: http://anatomyjournal.ir/article-1-416-en.html
URL: http://anatomyjournal.ir/article-1-416-en.html
1- Department, Shahid Beheshti Medical Science University, Tehran, Iran.
Abstract: (686 Views)
Purpose: In this study, TEM was used to asses the ultra structural effects of Cd on Photoreceptor and Ganglionic cells of mouce retinal layer.
Materials and Methods: 30 mice hi1Vebeen used in three groups (experimental I, II & control). On 9th day of gestation, experimental groups have received a single IP injection of Cadmium- chlorid (Cd C12) solution in saline, 3 mg/kg and 5 mg/kg respectively and control group received only distilled water. The mice were euthanized on day 15 of gestation. Specimens for TEM were prepared.
Results: External fragment shortness of photoreceptors, apoptotic nuclei, heterochromatic nuclei, deletion of nucleous membrane, invisible nucleolus, and mitochondrial changes in apoptotic cells were observed in experimental groups.
Conclusion: Cadmium exposure causes apoptotic changes in Photoreceptors and Ganglionic cells.
Materials and Methods: 30 mice hi1Vebeen used in three groups (experimental I, II & control). On 9th day of gestation, experimental groups have received a single IP injection of Cadmium- chlorid (Cd C12) solution in saline, 3 mg/kg and 5 mg/kg respectively and control group received only distilled water. The mice were euthanized on day 15 of gestation. Specimens for TEM were prepared.
Results: External fragment shortness of photoreceptors, apoptotic nuclei, heterochromatic nuclei, deletion of nucleous membrane, invisible nucleolus, and mitochondrial changes in apoptotic cells were observed in experimental groups.
Conclusion: Cadmium exposure causes apoptotic changes in Photoreceptors and Ganglionic cells.
Type of Study: Original |
Subject:
Morphometry
Received: 2021/12/26 | Accepted: 2005/10/18 | Published: 2005/10/18
Received: 2021/12/26 | Accepted: 2005/10/18 | Published: 2005/10/18
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
Contact Information
Anatomical Sciences Journal (ASJ)
Negah Institute for Scientific Communication, No.15, Na'eemi St., Mirzaye Shirazi St., Tehran, Iran.
Publisher Tel : +9821 4535 5555;
+9821 4535 5000
Website: http://www.anatomyjournal.ir/
E-mail: anatomyjournal@gmail.com
