Volume 2, Issue 2 (Summer 2004)                   ASJ 2004, 2(2): 1-11 | Back to browse issues page

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Bahar Vand H, Azar Nia M, Parivar K, Kazemi Ashtiani S. The Effect of Cardio Gel and Matrigel on the Ultrastructure of Cardiomyocytes Derived From Mouse Embryonic Stem Cells. ASJ 2004; 2 (2) :1-11
URL: http://anatomyjournal.ir/article-1-374-en.html
The Effect of Cardio Gel and Matrigel on the Ultrastructure of Cardiomyocytes Derived From Mouse Embryonic Stem Cells
Hosein Bahar Vand 1, Mehrnaz Azar Nia , Kazem Parivar , Saeed Kazemi Ashtiani
1- Stem Cell Group, Royant Research Institute, Tehran, Iran.
Abstract:   (941 Views)
Purpose: To investigate the effect of cardiogel and matrigel on the ultrastructure of embryonic stem cell-derived cardiomyocytes. ECM: Extracellular Matrix derived from cardiac fibroblasts (cardiogel), commercial extracellular matrix (matrigel) and control group (without ECM) were cultured for up to 21 days. Ultrastructural properties of cardiomyocytes were evaluated by transmitting electron microscopy (TEM). On the fourteenth day in cardiomyocytes showed cardiogel and on the twenty-first day of culture in all groups, the above structures appeared.
Conclusion: The results of this study showed that it is possible to produce mature cardiomyocytes (ultrastructurally) from stem cells Embryonic and fibroblast-derived cardiogels are effective in the faster maturation of embryonic stem cell-derived cardiomyocytes.
Keywords: Embryonic stem cells, Ultrastructure of cardiomyocyte, Cardiogel, Extracellular matrix
Full-Text [PDF 2375 kb]   (147 Downloads)    
Type of Study: Original | Subject: Morphometry
Received: 2021/12/26 | Accepted: 2004/07/20 | Published: 2004/07/20
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