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Volume 21, Issue 1 (Winter & Spring-InPress 2024)
ASJ 2024, 21(1): 0-0 |
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Salehi H, Sadeghi Z, Rahnama S, Sadeghpour Salamat S. RNA-loaded nanoparticles in breast cancer stem cell therapy: A review article. ASJ 2024; 21 (1)
URL: http://anatomyjournal.ir/article-1-624-en.html
URL: http://anatomyjournal.ir/article-1-624-en.html
1- Department of Anatomical Sciences and Reproductive Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
2- Department of Anatomical Sciences and Reproductive Biology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
3- Department of Anatomical Sciences and Reproductive Biology, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
2- Department of Anatomical Sciences and Reproductive Biology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
3- Department of Anatomical Sciences and Reproductive Biology, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
Abstract: (43 Views)
Breast cancer (BC) is one of the concerns of the health sector that affects many women every year. There are many methods to treat BC, however, many of these methods have harmful effects on healthy cells. Another problem for cancer treatment is the resistance of cancer cells to treatment, the short life of drugs for effectiveness, and the limited life of the drug in cancer site. Therefore, studies to develop cancer diagnosis and treatment methods are still ongoing. One of the new and interesting technologies for the treatment of cancers is the use of nanoparticles (NPs), which have opened a new window for the diagnosis and treatment of cancer in humans. These nanoparticles are used by binding to cells to carry various drugs and ligands to cancer cells, especially breast cancer stem cells (BCSCs). In this article, we review recent studies on the use of various metal nanoparticles, polymers, liposomes, and nanomicelles in the diagnosis and treatment of BCSCs. Although there are challenges and limitations in the use of nanosystems, it is hoped that by knowing more about their characteristics, we will soon witness a revolution in the diagnosis and treatment of BC. Therefore, this study explores various treatment approaches for BC and examines their limitations. Additionally, it introduces nanoparticles as a promising avenue for tumor diagnosis, imaging, and therapy, with a particular emphasis on RNA-loaded nanoparticles.
Type of Study: Review |
Subject:
Stem Cell
Received: 2024/09/25 | Accepted: 2025/05/25 | Published: 2024/04/14
Received: 2024/09/25 | Accepted: 2025/05/25 | Published: 2024/04/14
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