Volume 9, Issue 35 (Summer 2011)                   ASJ 2011, 9(35): 122-128 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Tarameshloo M, Norozian M, Mastari Farahani R, Fadaiee Fath Abadi F, Gazor R. A Study to Evaluate and Compare the Effects of Topical Administration of Aloe Vera Gel, Thyroid Hormone Cream and Silver Sulfadiazine Cream on Skin Incision in Wistar Rats. ASJ 2011; 9 (35) :122-128
URL: http://anatomyjournal.ir/article-1-531-en.html
A Study to Evaluate and Compare the Effects of Topical Administration of Aloe Vera Gel, Thyroid Hormone Cream and Silver Sulfadiazine Cream on Skin Incision in Wistar Rats
Mahsa Tarameshloo1 , Mohsen Norozian , Reza Mastari Farahani , Fatemeh Fadaiee Fath Abadi , Rohollah Gazor
Abstract:   (990 Views)
Purpose: The aim of present study was to assay and compare the effects of topical administration of Aloe Vera gel, thyroid hormone cream and silver sulfadiazine cream on wound healing in Wistar rats. Materials and Methods: In a randomized controlled trial, twelve Wistar male rats, 250 to 300 g, were divided randomly into 5 groups on the basis of the drug treatments: Aloe Vera gel (AV), thyroid hormone cream (TC), silver sulfadiazine 1% (S), vehicle (V) and control. To determine the efficacy of each treatment, a length measurement examination was used. The animals were examined on days 4,7and 14. The data was compared by One-way analysis of Variance (ANOVA) and Tukey posttest (5% level of significance) using SPSS 11.5 System.Results: The average percentage of healing was significantly improved in Aloe Vera gel and thyroid hormone cream groups on days 7 and 14 (p£0.05). No significant difference in average percentage of healing was observed among the silver sulfadiazine cream, vehicle and control groups.Conclusion: It seems, application of Aloe Vera gel and thyroid hormone cream are effective in healing skin incision in rats. These findings suggest that silver sulfadiazine cream has possibly no significant effect on wound healing in skin incision.
Keywords: Wound Healing, Aloe Vera, Thyroid Hormone, Silver Sulfadiazine, Topical Administration
Full-Text [PDF 387 kb]   (308 Downloads)    
Type of Study: Original | Subject: Morphometry
Received: 2021/12/30 | Accepted: 2011/08/28 | Published: 2011/08/28
Add your comments about this article : Your username or Email:
CAPTCHA
Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.