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Purpose: The aim of this study was to study the effect of three-dimensional model in learning the anatomy of middle ear. Materials and Methods: The study was conducted at Artesh University of Medical Sciences in 3 phases in 2007: 1- preparation of three-dimensional model with reference to the Gray's Anatomy for Students (2005-1st edition), 2- dividing medical and nursing students into 4 grouos accidentally, teaching with lecture and PowerPoint slides to control groups and additional teaching with threedimensional model to study groups, 3- taking similar pre-test and post-test exam and statistical analysis. Results: Analysis of pre-test and post-test scores in each group with t-test showed significant differences (p=0.000). There were not significant differences in respect to analysis of difference of pre-test and post-test scores between groups.Conclusion: Three-dimensional model had positive effect on anatomy learning of middle ear but it didn't cause significant difference in comparison with traditional educational method

Keywords: Anatomy, Education, Model, Middle Ear

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