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Purpose: To provide a comprehensive and precise research for population studies on the association of dermatoglyphic patterns on cleft lip/palate deficits. Materials and Methods: This was a case-control observational study that conducted in North Khorasan on 1386. Using a simple random sampling individuals with cleft/lip palate were allocated to case group and their matched health cases were considered as control. Palm and finger prints were done in the sample. In addition a-b, b-c and c-d counts, atd angel measurement and dermatoglyphics patterns of finger tips of both hands were made and the differences were compared between two groups. Palm prints were studied by an expert for quantitive and qualative characters and Statistical analysis was performed using by SPSS software. Results: Our findings showed that the group and sex did not affect the mean of a-b, b-c, c-d counts and mean of atd angle of right and left hands.The mean of a-b in females and males of both groups were similar (38.63 and 38.89 respectively). There were no significant differences between TABRC of males and females and right or left hands in both groups. The c-d count and atd angle of right hand was more than the left. The most frequent finger pattern in both hands was loop in both groups. There were no significant differences between two groups regarding the pattern of finger tips of both hands.Conclusion: In contrast of several studies that indicate there are special dermatoglyphic patterns in patients with cleft lip/palate, this study did not find any statistical differences between two groups regarding palm count and finger tips patterns of both hands. Since several environmental and hereditary factors would affect on the disease occurance, there is need to larger studies among different populations.

Keywords: Dermatoglyphic, Cleft Lip, Cleft Palate, Palm Print, Finger Tip Pattern

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