fa Morphometry Morphometry Original Original <strong>Purpose</strong>: In this study, TEM was used to asses the ultra structural effects of Cd on Photoreceptor and Ganglionic cells of mouce retinal layer.<br> <strong>Materials and Methods</strong>: 30 mice hi1Vebeen used in three groups (experimental I, II & control). On 9th day of gestation, experimental groups have received a single IP injection of Cadmium- chlorid (Cd C12) solution in saline, 3 mg/kg and 5 mg/kg respectively and control group received only distilled water. The mice were euthanized on day 15 of gestation. Specimens for TEM were prepared.<br> <strong>Results</strong>: External fragment shortness of photoreceptors, apoptotic nuclei, heterochromatic nuclei, deletion of nucleous membrane, invisible nucleolus, and mitochondrial changes in apoptotic cells were observed in experimental groups.<br> <strong>Conclusion</strong>: Cadmium exposure causes apoptotic changes in Photoreceptors and Ganglionic cells. Cadmium, Ultrastructure, Retina, TEM, Mice 163 171 http://anatomyjournal.ir/browse.php?a_code=A-10-304-111&slc_lang=fa&sid=1 Yoosef Sadeghi 10031947532846006930 10031947532846006930 Yes Department, Shahid Beheshti Medical Science University, Tehran, Iran. Abbas Piryaee 10031947532846006931 10031947532846006931 No Sahar Almasi Tork 10031947532846006932 10031947532846006932 No Amrollah Roozbehi 10031947532846006933 10031947532846006933 No