fa Morphometry Morphometry Original Original <strong>Purpose</strong>: Survey of protective effects of Ghazzayaghi (Falcaria vulgaris) extract against ethanol-induced peptic ulcer in rat.<br> <strong>Materials and Methods</strong>: Thirty-five young male rats (NMRI); 200-250gr weight divided in to five groups (7 Rats/group), the groups were treated with: distilled water 10kg in Control negative group, 50mg/kg ranitidine in control positives group, and three case groups were treated with 50, 100, 150-mg/kg extract by gavages, all groups were treated with 50% ethanol (10 mg/kg), and after one hour, all rat were killed and dissected. The stomach cut in greater curvatures and ulcer index was defined. Then, the stomachs were fixed and after tissue processing, 5-6, mm sections prepared for H.E staining and histological study and microscopic ulcer index.<br> <strong>Results</strong>: 70% ethanol extracts of Gazzayaghi with 50,100mg/kg body weight, significantly (P<0.05) decreased stomach ulcer index, and curative ratio for 50,100,150mg/kg were 55.9%, 76.9% and 80.25% respectively. Microscopic ulcer index with this three doses were reduced significantly (P<0.05) and curative ratio were 53.52%, 69.48% and 83.82% respectively.<br> <strong>Conclusion</strong>: The plant extracts have effective protective effect against gastric ulcer induced by ethanol. Gastric ulcer, Falcaria vulgaris, Protective effect, Ulcer index 75 81 http://anatomyjournal.ir/browse.php?a_code=A-10-304-92&slc_lang=fa&sid=1 Mozafar Khazaei 10031947532846006877 10031947532846006877 Yes Anatomy Department, Medical Sciences Kermanshah University, Kermanshah, Iran. Hosein Salehi 10031947532846006878 10031947532846006878 No Rostam Ghorbani 10031947532846006879 10031947532846006879 No